Mass Spectrometry Facility

The ABC hosts a large and well-equipped analytical facility for high throughput 'omic studies, including proteomics, metabolomics and nucleic acid analysis. A range of tandem mass spectrometers is available, including a maXis ultra high resolution ToF instrument and an Amazon Ion Trap with ETD (Bruker Daltonics). All instruments are interfaced with online nano/capillary high-performance liquid chromatography. In addition a number of HPLC and new UPLC instruments support a wide range of bioseparations including peptides, proteins and nucleic acids. Metabolite data can be acquired on a Thermo Finnigan TRACE DSQ GC-MS system (Thermo Scientific), which combines the high separation efficiency and resolution of capillary GC necessary with the high sensitivity of mass selective detection for complex metabolite profiling.